Includes bibliographical references and index.

Part I : Introduction. Biological research in toxicology --
Development of the field of toxicology --
Toxicology terms and how they relate to organisms --
Hazard, exposure, and risk modeling --
Part II : Toxic reactions of cells. Absorption and transport of toxicants through membranes : toxic damage to membranes --
Receptor-mediated toxicities on the outside of cells --
Detoxication and activation by cells : metabolism of the original toxicant --
Damage to cytosolic and endoplasmic reticulum activities --
Damage to mitochondrial and chloroplast activities --
Damage to nuclear structures/ DNA : mutagenesis and carcinogenesis --
Selective genetic sensitivity of cells to toxicants --
Nutritional toxicity and sensitivity --
Part III : Toxic reactions of tissues / organs. Routes of administration and which organs are most likely impacted based on route and toxicokinetic models --
Forensic toxicity testing --
The skin and eye : most likely exposure routes and toxicities due to contact exposure and dose toxicities --
Gastrointestinal system toxicity and oral exposure (GI tract, pancreas, liver) --
The lung and gill exposures representing toxic concentrations --
model for environmental toxicology --
The cardiovascular system as conduit for a dose becoming a dosage : exposure and toxicities --
Bone marrow and immune organ toxicity via lymphatic and blood transport --
The nervous system and exposure to lipophilic toxicants or transported neurotoxic agents --
Toxicity to neuroendocrine organs and endocrine disruption --
Toxicity to reproductive organs and developmental toxicity --
Excretion of hydrophilic toxicants and metabolites and kidney toxicity --
Part IV : Toxic reactions of ecosystems. Dispersion modeling in air, water, and soil : likely route of exposure and most sensitive organism based on dispersion and concentration --
Agricultural chemicals (pesticides and fertilizers) : exposure and impacts --
Industrial chemicals that biodegrade : organic chemical exposures and impacts --
Industrial chemicals that change lipophilicity but do not biodegrade : metal impacts --
Industrial chemicals that cause atmospheric changes and direct versus indirect toxicity : gases, vapors, aerosols, and radiation --
Toxicity of pharmaceuticals and personal care products (PPCPs) into water --
Part V : Biological toxicants. Venoms and injection toxicity versus poisonous animals or cells and ingestion or contact toxicity --
Poisonous plants or plant cells and ingestion or contact toxicity.

College of Health Sciences Bachelor of Science in Medical Technology

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