Applied biopharmaceutics & pharmacokinetics / Leon Shargel; Andrew B C Yu; Susanna Wu-Pong.
By: Shargel, Leon.
Contributor(s): Andrew B C Yu | Susanna Wu-Pong.
New York : McGraw-Hill, ©2013Edition: 6th ed.Description: xviii, 811 p. : ill. ; 25 cm.ISBN: 9781259071409.Subject(s): Biopharmaceutics | Pharmacokinetics | Models, ChemicalDDC classification: 615.7/Sh23 Other classification: CONItem type | Current location | Collection | Call number | Status | Date due | Barcode |
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Books | College Library General Circulation Section | GC | CON 615.7/Sh23 (Browse shelf) | Available | 79927 |
Browsing College Library Shelves , Shelving location: General Circulation Section , Collection code: GC Close shelf browser
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CON 615.58/K29 Pharmacology : | CON 615.58/K29 Pharmacology : | CON 615.58/R93 Community pharmacy : | CON 615.7/Sh23 Applied biopharmaceutics & pharmacokinetics / | CON 615.854/G89 Nutritional foundations and clinical applications : | CON 615.854/G89 Nutritional foundations and clinical applications : | CON 616.047/N14 Pathophysiology for nurses at a glance / |
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease -- Physiologic pharmacokinetic models, mean residence time, and statistical moment theory.
A textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics. It provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy.
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