To assess the use of research-based information among leaders in the local public health system. We conducted a mailed survey of county commissioners and directors, and selected managers (n=591) of all local public health agencies located in Minnesota. Forty-nine percent of respondents reported not using research information in making decisions about priority areas. The most common ways of accessing research information were by: (1) reading a research article, (2) through a state/federal health agency, or (3) attending conferences. However, these methods varied from those reported as the most effective ways for accessing research information, which included: (1) having a summary of journal articles regularly sent to them, (2) having funding agencies provide research information, and (3) through a staff-prepared summary. Findings suggest that while many agency leaders use research evidence in public health practice, there is room for improvement. To increase use of research information, effective methods for disseminating research need to be identified, evaluated, and broadly used.