Antibacterial properties of andrographis paniculata (serpentina) and sitex negundo (lagundi) in crude extracts against staphylococcus aureus and klebsiella pneumoniae/ (Record no. 138779)
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| 000 -LEADER | |
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| fixed length control field | 02826nam a22002177a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250523090817.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250508b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | HNU |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Placement Code | Th |
| Classification number | 615.321 An62 ©2025 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dolauta, Ma. Kreisell Lyn F.,et.al. |
| 245 ## - TITLE STATEMENT | |
| Title | Antibacterial properties of andrographis paniculata (serpentina) and sitex negundo (lagundi) in crude extracts against staphylococcus aureus and klebsiella pneumoniae/ |
| Statement of responsibility, etc. | Ma. Kreisell Lyn F. Dolauta; Sheally Zean B. Doydora; Jamil D. Laus; Jessele Gwyneth Eve B. Panase; Hannah Fatima E. Plazos; Lleod Mar S. Rulona.-- |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | [Tagbilaran City, Bohol]: |
| Name of producer, publisher, distributor, manufacturer | [Holy Name University], |
| Date of production, publication, distribution, manufacture, or copyright notice | [©2025]. |
| 336 ## - CONTENT TYPE | |
| Source | text |
| Content type term | rdacontent |
| 337 ## - MEDIA TYPE | |
| Source | unmediated |
| Media type term | rdamedia |
| 338 ## - CARRIER TYPE | |
| Source | volume |
| Carrier type term | rdacarrier |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Abstract: This study investigated the phytochemical composition and the antibacterial properties of Andrographis paniculata (serpentina) and Vitex negundo (lagundi) in crude extracts with various concentrations: 100%, 80%, 60%, and 20%, against Staphylococcus aureus and Klebsiella pneumoniae. Standard techniques revealed significant phytochemicals such as alkaloids, cardiac glycosides, flavonoids, phenols, saponins, and tannins. The antibacterial properties were assessed using disk diffusion method and broth microdilution method, which determined the zone of inhibition and minimum inhibitory concentration, respectively, and results were then compared with those of amoxicillin and gentamicin. Serpentina and lagundi extracts at all concentrations showed minimal zone of inhibition, whereas the mixture of both plants exhibited the highest zone of inhibition against Staphylococcus aureus. On the contrary, none of the plant extracts, at any concentration, exhibited zones of inhibition against Klebsiella pneumoniae. The lack of antibacterial property was disbarred in broth microdilution, where all crude leaf extracts showed inhibition against the bacteria. The discrepancy could be attributed to several fact, including the difference of medium used in the two methods. Statistical analysis employed one-way analysis of variance (ANOVA) to assess the significant difference between the experimental group and the controlled group, resulting to a p-value>0.05. Thus, a concentration-dependent relationship was observed, with higher concentrations of the extracts leading to greater bacterial inhibition, emphasizing the therapeutic potential in combating bacterial infections. Based on the findings, it was recommended that further studies to investigate the problems and/or factors that led to discrepancy between the disk diffusion method and the broth microdilution method. |
| 521 ## - TARGET AUDIENCE NOTE | |
| Target audience note | College of Health Sciences |
| Source | Bachelor of Science in Medical Technology |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicinal plants |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Theses |
| Classification part | 600-699 |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Non-public note | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | FIL | College Library | College Library | Theses Section | 05/08/2025 | Donation | Th 615.321 An62 2025 | TH02789 | 06/20/2025 | 05/08/2025 | tubac | Theses |
