TY  - BOOK
AU  - Lim,Henry C.
AU  - Shin,Hwa Sung
TI  - Fed-batch cultures: principles and applications of semi-batch bioreactors 
T2  - Cambridge series in chemical engineering
SN  - 9781139018777 (ebook)
AV  - TP248.25.B55 L56 2013
U1  - 660/.6 23
PY  - 2013///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Bioreactors
N1  - Title from publisher's bibliographic system (viewed on 05 Oct 2015); Introduction to fed-batch bioreactors -- Idealised reactors and fed-batch reactors -- Maximisation of reaction rates and fed-batch operation -- Phenomena that favour fed-batch operations -- Classification and characteristics of fed-batch cultures -- Models based on mass balance equations -- Non-equation-based models -- Experimental determination of specific rates -- Optimization via Pontryagin's maximum principle -- Computational techniques -- Optimization of single and multiple isothermal reactions -- Optimization of fed-batch cultures for cell mass production -- Optimization of fed-batch cultures for metabolites -- Simple, intuitive adaptive optimization -- Measurements, estimation and control -- Feasibility assessment and implementable feed rates
N2  - Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal and sub-optimal fed-batch operations. Numerous examples are provided to illustrate the application of optimal fed-batch cultures. This unique book, by world experts with decades of research and industrial experience, is a must for researchers and industrial practitioners of fed-batch processes (modeling, control and optimization) in biotechnology, fermentation, food, pharmaceuticals and waste treatment industries
UR  - https://doi.org/10.1017/CBO9781139018777
ER  -